Serum S100B: A proxy marker for grey and white matter status in the absence and presence of (increased risk of) psychotic disorder?

S100B is a protein with dose-dependent neurotrophic and neurotoxic effects. Whether S100B in psychotic disorder mirrors pathophysiological mechanisms (which elicit exacerbation of disease) or compensatory action is unclear, as is its validity as a proxy marker for brain status. Insight may be gained...

Full description

Bibliographic Details
Main Authors: Christine van der Leeuw, Sanne Peeters, Ed Gronenschild, Stijn Michielse, Marcel Verbeek, Paul Menheere, Jim van Os, Machteld Marcelis, Genetic Risk and Outcome in Psychosis (G.R.O.U.P.)
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5373815?pdf=render