Impaired Insulin/IGF Signaling in Experimental Alcohol-Related Myopathy

Impaired Insulin/IGF Signaling in Experimental Alcohol-Related Myopathy

Alcohol-related myopathy (Alc-M) is highly prevalent among heavy drinkers, although its pathogenesis is not well understood. We hypothesize that Alc-M is mediated by combined effects of insulin/IGF resistance and oxidative stress, similar to the effects of ethanol on liver and brain. We tested this...

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Bibliographic Details
Main Authors: Elizabeth Silbermann, Fusun Gundogan, Suzanne M. de la Monte, Ming Tong, Tran Le, Van Anh Nguyen
Format: Article
Language:English
Published: MDPI AG 2012-08-01
Series:Nutrients
Subjects:
alcohol
myopathy
insulin resistance
signal transduction
experimental model
multiplex ELISA
Akt pathway
gene expression
acetylcholine
oxidative stress
mitochondrial dysfunction
Online Access:http://www.mdpi.com/2072-6643/4/8/1058

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http://www.mdpi.com/2072-6643/4/8/1058

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