Bacterial c-di-GMP Affects Hematopoietic Stem/Progenitors and Their Niches through STING

Upon systemic bacterial infection, hematopoietic stem and progenitor cells (HSPCs) migrate to the periphery in order to supply a sufficient number of immune cells. Although pathogen-associated molecular patterns reportedly mediate HSPC activation, how HSPCs detect pathogen invasion in vivo remains e...

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Bibliographic Details
Main Authors: Hiroshi Kobayashi, Chiharu I. Kobayashi, Ayako Nakamura-Ishizu, Daiki Karigane, Hiroshi Haeno, Kimiyo N. Yamamoto, Taku Sato, Toshiaki Ohteki, Yoshihiro Hayakawa, Glen N. Barber, Mineo Kurokawa, Toshio Suda, Keiyo Takubo
Format: Article
Language:English
Published: Elsevier 2015-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124715002582