Distinct Stromal and Immune Features Collectively Contribute to Long-Term Survival in Pancreatic Cancer

Distinct Stromal and Immune Features Collectively Contribute to Long-Term Survival in Pancreatic Cancer

Background: The aggressive biology and treatment refractory nature of pancreatic ductal adenocarcinoma (PDAC) significantly limits long-term survival. Examining the tumor microenvironment (TME) of long-term survivors (LTS) of PDAC offers the potential of unveiling novel biological insights and thera...

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Bibliographic Details
Main Authors: Hassan Sadozai, Animesh Acharjee, Serenella Eppenberger-Castori, Beat Gloor, Thomas Gruber, Mirjam Schenk, Eva Karamitopoulou
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
PDAC–pancreatic ductal adenocarcinoma
long term survival
tumor associated macrophage (TAM)
cancer associated fibroblast (CAF)
tumor microenvironment (TME)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.643529/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.643529/full

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