Can certain genotypes predispose to poor asthma control in children? A pharmacogenetic study of 9 candidate genes in children with difficult asthma.

OBJECTIVE:We tested the hypothesis that patients with difficult asthma have an increased frequency of certain genotypes that predispose them to asthma exacerbations and poor asthma control. METHODS:A total of 180 Caucasian children with confirmed asthma diagnosis were selected from two phenotypic gr...

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Bibliographic Details
Main Authors: Basima Almomani, Ahmed F Hawwa, Jeffrey S Millership, Liam Heaney, Isabella Douglas, James C McElnay, Michael D Shields
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3616093?pdf=render