Enrichment of low abundance DNA/RNA by oligonucleotide-clicked iron oxide nanoparticles

Abstract Detection of low abundance target DNA/RNA for clinical or research purposes is challenging because the target sequences can be hidden under a large background of human genomic or non-human metagenomic sequences. We describe a probe-based capture method to enrich for target sequences with DN...

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Bibliographic Details
Main Authors: Fereshte Damavandi, Weiwei Wang, Wei-Zheng Shen, Sibel Cetinel, Tracy Jordan, Juan Jovel, Carlo Montemagno, Gane Ka-Shu Wong
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-92376-9