Follistatin Alleviates Synovitis and Articular Cartilage Degeneration Induced by Carrageenan

Activins are proinflammatory cytokines which belong to the TGFβ superfamily. Follistatin is an extracellular decoy receptor for activins. Since both activins and follistatin are expressed in articular cartilage, we hypothesized that activin-follistatin signaling participates in the process of joint...

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Bibliographic Details
Main Authors: Jun Yamada, Kunikazu Tsuji, Kazumasa Miyatake, Yu Matsukura, Kahaer Abula, Makiko Inoue, Ichiro Sekiya, Takeshi Muneta
Format: Article
Language:English
Published: Hindawi Limited 2014-01-01
Series:International Journal of Inflammation
Online Access:http://dx.doi.org/10.1155/2014/959271