HIV-Exposed Uninfected Infants Have Increased Regulatory T Cells That Correlate With Decreased T Cell Function

HIV-Exposed Uninfected Infants Have Increased Regulatory T Cells That Correlate With Decreased T Cell Function

Background: HIV-exposed uninfected infants (HEU) are at higher risk of severe infections, hospitalizations and death compared with HIV-unexposed uninfected infants (HUU), but the immune deficit underlying it is not known. To address this gap, we investigated T cell functionality and its relationship...

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Bibliographic Details
Main Authors: Emilie Jalbert, Kayla M. Williamson, Miranda E. Kroehl, Michael J. Johnson, Clare Cutland, Shabir A. Madhi, Marta C. Nunes, Adriana Weinberg
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Immunology
Subjects:
HIV-exposed uninfected infants
regulatory T cells
T cell function
antigen presenting cells
T cell differentiation
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00595/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.00595/full

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