Expression profiling of chromatin-modifying enzymes and global DNA methylation in CD4+ T cells from patients with chronic HIV infection at different HIV control and progression states

Expression profiling of chromatin-modifying enzymes and global DNA methylation in CD4+ T cells from patients with chronic HIV infection at different HIV control and progression states

Abstract Background Integration of human immunodeficiency virus type 1 (HIV-1) into the host genome causes global disruption of the chromatin environment. The abundance level of various chromatin-modifying enzymes produces these alterations and affects both the provirus and cellular gene expression....

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Bibliographic Details
Main Authors: Roberta Nicoleta Bogoi, Alicia de Pablo, Eulalia Valencia, Luz Martín-Carbonero, Victoria Moreno, Helem Haydee Vilchez-Rueda, Victor Asensi, Rosa Rodriguez, Victor Toledano, Berta Rodés
Format: Article
Language:English
Published: BMC 2018-02-01
Series:Clinical Epigenetics
Subjects:
HIV
Progression
Epigenetics
Methyltransferases
HDAC
Chromatin-modifying enzymes
Online Access:http://link.springer.com/article/10.1186/s13148-018-0448-5

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http://link.springer.com/article/10.1186/s13148-018-0448-5

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