miR-548e Sponged by ZFAS1 Regulates Metastasis and Cisplatin Resistance of OC by Targeting CXCR4 and let-7a/BCL-XL/S Signaling Axis

miR-548e Sponged by ZFAS1 Regulates Metastasis and Cisplatin Resistance of OC by Targeting CXCR4 and let-7a/BCL-XL/S Signaling Axis

Ovarian cancer (OC) is a severe malignancy featuring a poor prognosis due to rapid metastasis and chemotherapy resistance. In this study, we extensively investigated the upstream and downstream mechanisms of miR-548e in regulating OC progression and cisplatin resistance. Our results indicated that Z...

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Bibliographic Details
Main Authors: Jing Zhang, Li-Ni Quan, Qiu Meng, Hai-Yan Wang, Jie Wang, Pin Yu, Jian-Tao Fu, Ying-Jia Li, Jin Chen, Hong Cheng, Qing-Ping Wu, Xin-Rong Yu, Hong-Ye Yun, Shou-Guo Huang
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
ovarian cancer
ZFAS1
miR-548e
CXCR4
Let-7a
metastasis
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120301049

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http://www.sciencedirect.com/science/article/pii/S2162253120301049

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