Asiatic Acid Prevents the Deleterious Effects of Valproic Acid on Cognition and Hippocampal Cell Proliferation and Survival

Asiatic Acid Prevents the Deleterious Effects of Valproic Acid on Cognition and Hippocampal Cell Proliferation and Survival

Valproic acid (VPA) is commonly prescribed as an anticonvulsant and mood stabilizer used in the treatment of epilepsy and bipolar disorder. A recent study has demonstrated that VPA reduces histone deacetylase (HDAC) activity, an action which is believed to contribute to the effects of VPA on neural...

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Bibliographic Details
Main Authors: Jariya Umka Welbat, Apiwat Sirichoat, Wunnee Chaijaroonkhanarak, Parichat Prachaney, Wanassanun Pannangrong, Poungrat Pakdeechote, Bungorn Sripanidkulchai, Peter Wigmore
Format: Article
Language:English
Published: MDPI AG 2016-05-01
Series:Nutrients
Subjects:
valproic acid
Asiatic acid
neurogenesis
spatial memory
Online Access:http://www.mdpi.com/2072-6643/8/5/303

Internet

http://www.mdpi.com/2072-6643/8/5/303

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