Allelic and genotype frequencies of major CYP2B6 polymorphisms in the Pakistani population

Abstract Background Cytochrome P450 (CYP2B6) is an important enzyme that metabolizes about 3.0% of therapeutic drugs. Drugs metabolized mainly by CYP2B6 include artemisinin, bupropion, cyclophosphamide, efavirenz, ketamine, and methadone. The genetic polymorphisms in the CYP2B6 gene have earlier bee...

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Bibliographic Details
Main Authors: Sagheer Ahmed, Saeed Khan, Kholood Janjua, Imran Imran, Arif Ullah Khan
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
Online Access:https://doi.org/10.1002/mgg3.1527