Divergent Effects of Dioxin- or Non-Dioxin-Like Polychlorinated Biphenyls on the Apoptosis of Primary Cell Culture from the Mouse Pituitary Gland.

Polychlorinated biphenyls (PCBs) can disrupt the endocrine function, promote neoplasms and regulate apoptosis in some tissues; however, it is unknown whether PCBs can affect the apoptosis of pituitary cells. The study evaluated the effect of PCBs on the apoptosis of normal pituitary cells and the un...

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Main Authors: Francesco Raggi, Dania Russo, Claudio Urbani, Chiara Sardella, Luca Manetti, Daniele Cappellani, Isabella Lupi, Luca Tomisti, Enio Martino, Claudio Marcocci, Fausto Bogazzi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4709048?pdf=render