Commitment of protein p53 and amyloid-beta peptide (Aβ) in aging of human cerebellum

Commitment of protein p53 and amyloid-beta peptide (Aβ) in aging of human cerebellum

Protein p53 is known to induce the cell cycle arrest and apoptosis in response to a variety of cellular distress signals and DNA damage. A recent study has demonstrated that in blood cells of aging subjects, p53 may induce early pathological changes that precede the amyloidogenic cascade. However, i...

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Bibliographic Details
Main Authors: Danuta Maślińska, Milena Laure-Kamionowska, Dariusz Szukiewicz, Sławomir Maśliński, Krystyna Księżopolska-Orłowska
Format: Article
Language:English
Published: Termedia Publishing House 2017-06-01
Series:Folia Neuropathologica
Subjects:
<i>amyloid-beta (Aβ) deposits
aging
cerebellum
p53
neurodegeneration</i>
Online Access:https://www.termedia.pl/Commitment-of-protein-p53-and-amyloid-beta-peptide-A-in-aging-of-human-cerebellum,20,30155,1,1.html

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https://www.termedia.pl/Commitment-of-protein-p53-and-amyloid-beta-peptide-A-in-aging-of-human-cerebellum,20,30155,1,1.html

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