Hepatic-Specific Decrease in the Expression of Selenoenzymes and Factors Essential for Selenium Processing After Endotoxemia

Hepatic-Specific Decrease in the Expression of Selenoenzymes and Factors Essential for Selenium Processing After Endotoxemia

BackgroundSelenium (Se) levels decrease in the circulation during acute inflammatory states and sepsis, and are inversely associated with morbidity and mortality. A more specific understanding of where selenoproteins and Se processing are compromised during insult is needed. We investigated the acut...

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Bibliographic Details
Main Authors: Laura G. Sherlock, Kara Sjostrom, Lei Sian, Cassidy Delaney, Trent E. Tipple, Nancy F. Krebs, Eva Nozik-Grayck, Clyde J. Wright
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Immunology
Subjects:
selenium
selenoenzymes
liver
endotoxemia
selenoprotein P
selenocysteine processing
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.595282/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.595282/full

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