mTORC2 Signaling Selectively Regulates the Generation and Function of Tissue-Resident Peritoneal Macrophages

mTORC2 Signaling Selectively Regulates the Generation and Function of Tissue-Resident Peritoneal Macrophages

Tissue-resident macrophages play critical roles in sentinel and homeostatic functions as well as in promoting inflammation and immunity. It has become clear that the generation of these cells is highly dependent upon tissue-specific cues derived from the microenvironment that, in turn, regulate uniq...

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Bibliographic Details
Main Authors: Min-Hee Oh, Samuel L. Collins, Im-Hong Sun, Ada J. Tam, Chirag H. Patel, Matthew L. Arwood, Yee Chan-Li, Jonathan D. Powell, Maureen R. Horton
Format: Article
Language:English
Published: Elsevier 2017-09-01
Series:Cell Reports
Subjects:
tissue-resident macrophage
mTORC2
FOXO1
GATA6
metabolism
mTOR
AKT
peritoneal macrophage
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717311713

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http://www.sciencedirect.com/science/article/pii/S2211124717311713

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