Repopulation of Human Origin Hepatocyte Progenitor-Like Cell Line, THLE-5b, in the SCID Mouse Liver under p21-Mediated Cell Growth-Arresting Conditions

The in vivo repopulation of hepatocytes depends on donor cell growth potential and recipient conditioning. We herein demonstrate the successful cell transplantation of a human hepatocyte cell line, THLE-5b, into the SCID mouse liver by means of a rather mild conditioning using a 55% hepatectomy and...

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Bibliographic Details
Main Authors: Shin Enosawa, Taisuke Yamazaki, Hitoshi Kohsaka, Takayoshi Tokiwa
Format: Article
Language:English
Published: SAGE Publishing 2012-03-01
Series:Cell Transplantation
Online Access:https://doi.org/10.3727/096368911X605358