Radiosensitization of breast cancer cells using AS1411 aptamer-conjugated gold nanoparticles

Radiosensitization of breast cancer cells using AS1411 aptamer-conjugated gold nanoparticles

Abstract Background Gold nanoparticles (GNPs) have been used to sensitize cancer cells and enhance the absorbed dose delivered to such cells. Active targeting can provide specific effect and higher uptake of the GNPs in the tumor cells, while having small effect on healthy cells. The aim of this stu...

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Bibliographic Details
Main Authors: Somayeh Sadat Mehrnia, Bijan Hashemi, Seyed Javad Mowla, Maryam Nikkhah, Azim Arbabi
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Radiation Oncology
Subjects:
Gold nanoparticles
Radiosensitizer
Aptamer AS1411
Breast cancer cells
Mammosphere
4 MeV electron beam
Online Access:https://doi.org/10.1186/s13014-021-01751-3

Internet

https://doi.org/10.1186/s13014-021-01751-3

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