Metabolic correction by pyruvate halts acquired epilepsy in multiple rodent models

Metabolic correction by pyruvate halts acquired epilepsy in multiple rodent models

Metabolic intervention strategy of epilepsy treatment has been gaining broader attention due to accumulated evidence that hypometabolism, manifested in humans as reduced brain glucose consumption, is a principal factor in acquired epilepsy. Therefore, targeting deficient energy metabolism may be an...

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Bibliographic Details
Main Authors: I. Popova, A. Malkov, A.I. Ivanov, E. Samokhina, S. Buldakova, O. Gubkina, A. Osypov, R.S. Muhammadiev, T. Zilberter, M. Molchanov, S. Paskevich, M. Zilberter, Y. Zilberter
Format: Article
Language:English
Published: Elsevier 2017-10-01
Series:Neurobiology of Disease
Subjects:
Energy metabolism
Glucose utilization
Tetanus toxin
Kindling
Alzheimer's disease epilepsy
Seizures
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996117301626

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http://www.sciencedirect.com/science/article/pii/S0969996117301626

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