Insights into deregulated TNF and IL-10 production in malaria: implications for understanding severe malarial anaemia

Insights into deregulated TNF and IL-10 production in malaria: implications for understanding severe malarial anaemia

<p>Abstract</p> <p>Background</p> <p>Severe malarial anaemia (SMA) is a major life-threatening complication of paediatric malaria. Protracted production of pro-inflammatory cytokines promoting erythrophagocytosis and depressing erythropoiesis is thought to play an impor...

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Bibliographic Details
Main Authors: Boeuf Philippe S, Loizon Séverine, Awandare Gordon A, Tetteh John KA, Addae Michael M, Adjei George O, Goka Bamenla, AL Kurtzhals Jørgen, Puijalon Odile, Hviid Lars, Akanmori Bartholomew D, Behr Charlotte
Format: Article
Language:English
Published: BMC 2012-08-01
Series:Malaria Journal
Subjects:
Malaria
Anaemia
Cerebral malaria
Severe malarial anaemia
Monocytes
T cells
CD69
HLA-DR
Monocyte de-activation, TNF
IL-10
Cytokines
Online Access:http://www.malariajournal.com/content/11/1/253

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http://www.malariajournal.com/content/11/1/253

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