HLA-B*13:01 as a Risk Allele for Antiepileptic Drugs-Induced Cutaneous Adverse Reactions: Higher Risk for Cross-Reactivity?

HLA-B*13:01 as a Risk Allele for Antiepileptic Drugs-Induced Cutaneous Adverse Reactions: Higher Risk for Cross-Reactivity?

Antiepileptic drugs frequently cause cutaneous adverse reactions (cADRs). Numerous studies have reported associations between human leukocyte antigen (HLA) alleles and cADRs caused by single antiepileptic drug in Southern Han Chinese people. However, the relationship between the HLA allele and cADRs...

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Bibliographic Details
Main Authors: Fu-Li Min, Bi-Jun Mao, Zhong-Zheng Zheng, Na He, Cui-Xia Fan, Rui-Yan Cai, Juan Wang, Yang-Mei Ou, Bing Qin, Wei-Ping Liao, Yong-Hong Yi, Ze Li, Yi-Wu Shi
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-06-01
Series:Frontiers in Neurology
Subjects:
antiepileptic drugs
cross-reactivity
HLA allele
HLA-B*13:01
genetic marker
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.00614/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2019.00614/full

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