Lemon exosome-like nanoparticles enhance stress survival of gut bacteria by RNase P-mediated specific tRNA decay

Summary: Diet and bile play critical roles in shaping gut microbiota, but the molecular mechanism underlying interplay with intestinal microbiota is unclear. Here, we showed that lemon-derived exosome-like nanoparticles (LELNs) enhance lactobacilli toleration to bile. To decipher the mechanism, we u...

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Bibliographic Details
Main Authors: Chao Lei, Yun Teng, Liqing He, Mohammed Sayed, Jingyao Mu, Fangyi Xu, Xiangcheng Zhang, Anil Kumar, Kumaran Sundaram, Mukesh K. Sriwastva, Lifeng Zhang, Shao-yu Chen, Wenke Feng, Shuangqin Zhang, Jun Yan, Juw Won Park, Michael L. Merchant, Xiang Zhang, Huang-Ge Zhang
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S258900422100479X