Hidden Aggregation Hot-Spots on Human Apolipoprotein E: A Structural Study

Hidden Aggregation Hot-Spots on Human Apolipoprotein E: A Structural Study

Human apolipoprotein E (apoE) is a major component of lipoprotein particles, and under physiological conditions, is involved in plasma cholesterol transport. Human apolipoprotein E found in three isoforms (E2; E3; E4) is a member of a family of apolipoproteins that under pathological conditions are...

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Bibliographic Details
Main Authors: Paraskevi L. Tsiolaki, Aikaterini D. Katsafana, Fotis A. Baltoumas, Nikolaos N. Louros, Vassiliki A. Iconomidou
Format: Article
Language:English
Published: MDPI AG 2019-05-01
Series:International Journal of Molecular Sciences
Subjects:
apolipoprotein E
amyloid fibrils
Alzheimer’s disease
Αβ oligomer
Online Access:https://www.mdpi.com/1422-0067/20/9/2274

Internet

https://www.mdpi.com/1422-0067/20/9/2274

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