One-pot and one-step automated radio-synthesis of [18F]AlF-FAPI-74 using a multi purpose synthesizer: a proof-of-concept experiment

One-pot and one-step automated radio-synthesis of [18F]AlF-FAPI-74 using a multi purpose synthesizer: a proof-of-concept experiment

Abstract Background Fibroblast activation protein (FAP) is overexpressed in the stroma of many types of cancer. [18F]AlF-FAPI-74 is a positron emission tomography tracer with high selectivity for FAP, which has already shown high accumulation within human tumors in clinical studies. However, [18F]Al...

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Bibliographic Details
Main Authors: Sadahiro Naka, Tadashi Watabe, Thomas Lindner, Jens Cardinale, Kenta Kurimoto, Melissa Moore, Mitsuaki Tatsumi, Yuriko Mori, Eku Shimosegawa, Frank Valla, Hiroki Kato, Frederik L. Giesel
Format: Article
Language:English
Published: SpringerOpen 2021-08-01
Series:EJNMMI Radiopharmacy and Chemistry
Subjects:
Positron emission tomography
Fibroblast activation protein
[18F]AlF-FAPI-74
Automated synthesis
Online Access:https://doi.org/10.1186/s41181-021-00142-z

Internet

https://doi.org/10.1186/s41181-021-00142-z

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