ABT-737 reverses the acquired radioresistance of breast cancer cells by targeting Bcl-2 and Bcl-xL

ABT-737 reverses the acquired radioresistance of breast cancer cells by targeting Bcl-2 and Bcl-xL

<p>Abstract</p> <p>Background</p> <p>Acquired radioresistance of cancer cells remains a fundamental barrier to attaining the maximal efficacy of radiotherapy for the treatment of breast cancer. Anti-apoptotic proteins, such as Bcl-2 and Bcl-xL, play an important role in...

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Bibliographic Details
Main Authors: Li Ji-Yu, Li Yu-Yang, Jin Wei, Yang Qing, Shao Zhi-Ming, Tian Xing-Song
Format: Article
Language:English
Published: BMC 2012-12-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
ABT-737
Breast cancer
Acquired radioresistance
Radiation
Bcl-2
Bcl-xL
Online Access:http://www.jeccr.com/content/31/1/102

Internet

http://www.jeccr.com/content/31/1/102

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