β-Asarone increases doxorubicin sensitivity by suppressing NF-κB signaling and abolishes doxorubicin-induced enrichment of stem-like population by destabilizing Bmi1

β-Asarone increases doxorubicin sensitivity by suppressing NF-κB signaling and abolishes doxorubicin-induced enrichment of stem-like population by destabilizing Bmi1

Abstract Background Lymphoma is one of the most common hematologic malignancy. Drug resistance is the main obstacle faced in lymphoma treatment. Cancer stem cells are considered as the source of tumor recurrence, metastasis and drug resistance. The β-Asarone, a low-toxicity compound from the traditi...

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Bibliographic Details
Main Authors: Li-Na Lv, Xiao-Chao Wang, Li-Ju Tao, Hong-Wen Li, Shu-You Li, Fei-Meng Zheng
Format: Article
Language:English
Published: BMC 2019-06-01
Series:Cancer Cell International
Subjects:
β-Asarone
Lymphoma
Natural compounds
Bmi1
Cancer stem cell
NF-κB
Online Access:http://link.springer.com/article/10.1186/s12935-019-0873-3

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http://link.springer.com/article/10.1186/s12935-019-0873-3

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