Anti-oncogenic activities exhibited by paracrine factors of MSCs can be mediated by modulation of KITLG and DKK1 genes in glioma SCs in vitro

Anti-oncogenic activities exhibited by paracrine factors of MSCs can be mediated by modulation of KITLG and DKK1 genes in glioma SCs in vitro

Cancer stem cells (CSCs) use their stemness properties to perpetuate their lineage and survive chemotherapy. Currently cell-based and cell-free therapies are under investigation to develop novel anti-cancer treatment modalities. We designed this study to investigate how cell extracts of mesenchymal...

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Bibliographic Details
Main Authors: Nazneen Aslam, Elham Abusharieh, Duaa Abuarqoub, Dema Ali, Dana Al-Hattab, Suha Wehaibi, Ban Al-Kurdi, Fatima Jamali, Walhan Alshaer, Hanan Jafar, Abdalla S. Awidi
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Molecular Therapy: Oncolytics
Subjects:
mesenchymal stem cells
glioma stem cells
gliospheres
conditioned media
WJ-MSCs
BM-MSCs
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770520301704

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http://www.sciencedirect.com/science/article/pii/S2372770520301704

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