Cellular and molecular mechanisms of PIK3CA-related vascular anomalies
The phosphoinositide 3-kinase (PI3K) pathway is a major mediator of growth factor signaling, cell proliferation and metabolism. Somatic gain-of-function mutations in PIK3CA, the catalytic subunit of PI3K, have recently been discovered in a number of vascular anomalies. The timing and origin of these...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Bioscientifica
2019-06-01
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| Series: | Vascular Biology |
| Subjects: | |
| Online Access: | https://vb.bioscientifica.com/view/journals/vb/1/1/VB-19-0016.xml |