Synthesis and Biological Evaluation of New Cholinesterase Inhibitors for Alzheimer’s Disease

Synthesis and Biological Evaluation of New Cholinesterase Inhibitors for Alzheimer’s Disease

Alzheimer’s disease (AD) is a neurodegenerative disorder mostly influencing the elderly, and causes death due to dementia. The main pathogenic feature connected with the progression of this multifactorial disease is the weakening of the cholinergic system in the brain. Cholinesterase (ChE)...

Full description

Bibliographic Details
Main Authors: Weiam Hussein, Begüm Nurpelin Sağlık, Serkan Levent, Büşra Korkut, Sinem Ilgın, Yusuf Özkay, Zafer Asım Kaplancıklı
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Molecules
Subjects:
Alzheimer’s disease
acetylcholinesterase
butyrylcholinesterase
9-aminoacridine
dithiocarbamate salts
docking study
Online Access:http://www.mdpi.com/1420-3049/23/8/2033

Internet

http://www.mdpi.com/1420-3049/23/8/2033

Similar Items