Splicing Regulators and Their Roles in Cancer Biology and Therapy

Alternative splicing allows cells to expand the encoding potential of their genomes. In this elegant mechanism, a single gene can yield protein isoforms with even antagonistic functions depending on the cellular physiological context. Alterations in splicing regulatory factors activity in cancer cel...

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Bibliographic Details
Main Authors: Maria Roméria da Silva, Gabriela Alves Moreira, Ronni Anderson Gonçalves da Silva, Éverton de Almeida Alves Barbosa, Raoni Pais Siqueira, Róbson Ricardo Teixera, Márcia Rogéria Almeida, Abelardo Silva Júnior, Juliana Lopes Rangel Fietto, Gustavo Costa Bressan
Format: Article
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/150514