Epigenetic characterization of CDKN1C in placenta samples from non-syndromic intrauterine growth restriction

The Cyclin-dependent kinase (CDK)-inhibitor 1C (CDKN1C) gene is expressed from the maternal allele and is located within the centromeric imprinted domain at chromosome 11p15. It is a negative regulator of proliferation, with loss-of-function mutations associated with the overgrowth disorder Beckwith...

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Bibliographic Details
Main Authors: David eMonk, Miriam eLópez-Abad, Isabel eIglesias-Platas
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-04-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00062/full