Anti-Apoptotic Effects of Lentiviral Vector Transduction Promote Increased Rituximab Tolerance in Cancerous B-Cells.

Diffuse large B-cell lymphoma (DLBCL) is characterized by great genetic and clinical heterogeneity which complicates prognostic prediction and influences treatment efficacy. The most common regimen, R-CHOP, consists of a combination of anthracycline- and immuno-based drugs including Rituximab. It re...

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Bibliographic Details
Main Authors: Benyamin Ranjbar, Louise Bechmann Krogh, Maria Bach Laursen, Maria Nascimento Primo, Sara Correia Marques, Karen Dybkær, Jacob Giehm Mikkelsen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4821607?pdf=render