Allosteric Regulation in the Ligand Binding Domain of Retinoic Acid Receptorγ.

Allosteric Regulation in the Ligand Binding Domain of Retinoic Acid Receptorγ.

Retinoic acid (RA) plays key roles in cell differentiation and growth arrest through nuclear retinoic acid receptors (RARs), which are ligand-dependent transcription factors. While the main trigger of RAR activation is the binding of RA, phosphorylation of the receptors has also emerged as an import...

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Bibliographic Details
Main Authors: Yassmine Chebaro, Serena Sirigu, Ismail Amal, Régis Lutzing, Roland H Stote, Cécile Rochette-Egly, Natacha Rochel, Annick Dejaegere
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5268703?pdf=render

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http://europepmc.org/articles/PMC5268703?pdf=render

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