A precisely regulated gene expression cassette potently modulates metastasis and survival in multiple solid cancers.
Successful tumor development and progression involves the complex interplay of both pro- and anti-oncogenic signaling pathways. Genetic components balancing these opposing activities are likely to require tight regulation, because even subtle alterations in their expression may disrupt this balance...
| Main Authors: | , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2008-07-01
|
| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC2444049?pdf=render |