Chromosomal copy number aberrations in colorectal metastases resemble their primary counterparts and differences are typically non-recurrent.

Chromosomal copy number aberrations in colorectal metastases resemble their primary counterparts and differences are typically non-recurrent.

The metastatic process is complex and remains a major obstacle in the management of colorectal cancer. To gain a better insight into the pathology of metastasis, we investigated genomic aberrations in a large cohort of matched colorectal cancer primaries and distant metastases from various sites by...

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Bibliographic Details
Main Authors: Leonie J M Mekenkamp, Josien C Haan, Daniëlle Israeli, Hendrik F B van Essen, Jeroen R Dijkstra, Patricia van Cleef, Cornelis J A Punt, Gerrit A Meijer, Iris D Nagtegaal, Bauke Ylstra
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3914793?pdf=render

Internet

http://europepmc.org/articles/PMC3914793?pdf=render

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