Chromosomal copy number aberrations in colorectal metastases resemble their primary counterparts and differences are typically non-recurrent.
The metastatic process is complex and remains a major obstacle in the management of colorectal cancer. To gain a better insight into the pathology of metastasis, we investigated genomic aberrations in a large cohort of matched colorectal cancer primaries and distant metastases from various sites by...
Main Authors: | Leonie J M Mekenkamp, Josien C Haan, Daniëlle Israeli, Hendrik F B van Essen, Jeroen R Dijkstra, Patricia van Cleef, Cornelis J A Punt, Gerrit A Meijer, Iris D Nagtegaal, Bauke Ylstra |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3914793?pdf=render |
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