Human embryoid bodies as a 3D tissue model of the extracellular matrix and α-dystroglycanopathies

The basal lamina is a specialized sheet of dense extracellular matrix (ECM) linked to the plasma membrane of specific cell types in their tissue context, which serves as a structural scaffold for organ genesis and maintenance. Disruption of the basal lamina and its functions is central to many disea...

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Bibliographic Details
Main Authors: Alec R. Nickolls, Michelle M. Lee, Kristen Zukosky, Barbara S. Mallon, Carsten G. Bönnemann
Format: Article
Language:English
Published: The Company of Biologists 2020-06-01
Series:Disease Models & Mechanisms
Subjects:
Online Access:http://dmm.biologists.org/content/13/6/dmm042986