The Role of Rare Coding Variants in Parkinson's Disease GWAS Loci

The Role of Rare Coding Variants in Parkinson's Disease GWAS Loci

Introduction: Genome-wide association studies (GWAS) have identified multiple loci associated with Parkinson's disease (PD) risk. The presence of rare variants within these loci that may account for the increased susceptibility requires further investigation.Methods: Using exome sequencing, we...

Full description

Bibliographic Details
Main Authors: Elisabeth Luisa Germer, Sophie Imhoff, Carles Vilariño-Güell, Meike Kasten, Philip Seibler, Norbert Brüggemann, International Parkinson’s Disease Genomics Consortium, Christine Klein, Joanne Trinh
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-12-01
Series:Frontiers in Neurology
Subjects:
Parkinson's disease
GWAS
rare variants association analyses
exome analysis
STAB1
SH3GL2
Online Access:https://www.frontiersin.org/article/10.3389/fneur.2019.01284/full

Internet

https://www.frontiersin.org/article/10.3389/fneur.2019.01284/full

Similar Items