Adenovirus-mediated siRNA targeting Bcl-xL inhibits proliferation, reduces invasion and enhances radiosensitivity of human colorectal cancer cells

<p>Abstract</p> <p>Introduction</p> <p>Bcl-xL, an important member of anti-apoptotic Bcl-2 family, plays critical roles in tumor progression and development. Previously, we have reported that overexpression of Bcl-xL was correlated with prognosis of colorectal cancer (C...

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Bibliographic Details
Main Authors: Lv Chengyu, Zhang Aiping, Sun Ming, Yang Jinsong, De Wei, Wang Zhaoxia
Format: Article
Language:English
Published: BMC 2011-10-01
Series:World Journal of Surgical Oncology
Online Access:http://www.wjso.com/content/9/1/117