Myostatin inactivation induces a similar muscle molecular signature in double-muscled cattle as in mice

Myostatin (MSTN), a member of the TGF-β superfamily, is a negative regulator of skeletal muscle mass. We have previously shown that the cell survival/apoptosis pathway is a downstream target of MSTN loss-of-function in mice through the regulation of the expression or abundance of many survival and a...

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Bibliographic Details
Main Authors: I. Chelh, B. Picard, J-F. Hocquette, I. Cassar-Malek
Format: Article
Language:English
Published: Elsevier 2011-01-01
Series:Animal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1751731110001862