Antibody Affinity Maturation in Fishes—Our Current Understanding

It has long been believed that fish lack antibody affinity maturation, in part because they were thought to lack germinal centers. Recent research done on sharks and bony fishes indicates that these early vertebrates are able to affinity mature their antibodies. This article reviews the functionalit...

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Bibliographic Details
Main Author: Brad G. Magor
Format: Article
Language:English
Published: MDPI AG 2015-07-01
Series:Biology
Subjects:
AID
Online Access:http://www.mdpi.com/2079-7737/4/3/512