Potential mechanisms underlying the protective effect of pregnancy against breast cancer: A focus on the IGF pathway

A first full term birth at an early age protects women against breast cancer by reducing lifetime risk by up to 50%. The underlying mechanism resulting in this protective effect remains unclear, but many avenues have been investigated, including lobular differentiation, cell fate, and stromal compos...

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Bibliographic Details
Main Author: Tiffany A Katz
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-10-01
Series:Frontiers in Oncology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2016.00228/full