Serum Metabolomics Associating With Circulating MicroRNA Profiles Reveal the Role of miR-383-5p in Rat Hippocampus Under Simulated Microgravity

Serum Metabolomics Associating With Circulating MicroRNA Profiles Reveal the Role of miR-383-5p in Rat Hippocampus Under Simulated Microgravity

Microgravity impacts various aspects of human health. Yet the mechanisms of spaceflight-induced health problems are not elucidated. Here, we mapped the fusion systemic analysis of the serum metabolome and the circulating microRNAome in a hindlimb unloading rat model to simulate microgravity. The res...

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Bibliographic Details
Main Authors: Hongyu Zhang, Jian Chen, Hailong Wang, Xin Lu, Kai Li, Chao Yang, Feng Wu, Zihan Xu, Huan Nie, Bai Ding, Zhifeng Guo, Yu Li, Jinfu Wang, Yinghui Li, Zhongquan Dai
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Physiology
Subjects:
microgravity
metabolome
miRNAome
miR-383-5p
aquaporin 4
hippocampus
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2020.00939/full

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https://www.frontiersin.org/article/10.3389/fphys.2020.00939/full

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