A Phospho-SIM in the Antiviral Protein PML is Required for Its Recruitment to HSV-1 Genomes

Herpes simplex virus type 1 (HSV-1) is a significant human pathogen that infects a large portion of the human population. Cells deploy a variety of defenses to limit the extent to which the virus can replicate. One such factor is the promyelocytic leukemia (PML) protein, the nucleating and organizin...

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Bibliographic Details
Main Authors: Miles C. Smith, Andrew C. Box, Jeffrey S. Haug, William S. Lane, David J. Davido
Format: Article
Language:English
Published: MDPI AG 2014-12-01
Series:Cells
Subjects:
PML
HSV
Online Access:http://www.mdpi.com/2073-4409/3/4/1131