The development of nasal polyp disease involves early nasal mucosal inflammation and remodelling.

Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by both a chronic inflammation and tissue remodelling; as indicated by extracellular matrix protein deposition, basement membrane thickening, goblet cell hyperplasia and subepithelial edema, with reduced vessels and glands. Although...

Full description

Bibliographic Details
Main Authors: Juan Meng, Peng Zhou, Yafeng Liu, Feng Liu, Xuelian Yi, Shixi Liu, Gabriele Holtappels, Claus Bachert, Nan Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3858290?pdf=render