Chromatin accessibility regulates chemotherapy-induced dormancy and reactivation

Chromatin accessibility regulates chemotherapy-induced dormancy and reactivation

Cisplatin-based chemotherapy remains the standard care for non-small cell lung cancer (NSCLC) patients. Relapse after chemotherapy-induced dormancy affects the overall survival of patients. The evolution of cancer cells under chemotherapy stress is regulated by transcription factors (TFs) with bindi...

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Bibliographic Details
Main Authors: Lujuan Wang, Qiu Peng, Na Yin, Yaohuan Xie, Jiaqi Xu, Anqi Chen, Junqi Yi, Jingqun Tang, Juanjuan Xiang
Format: Article
Language:English
Published: Elsevier 2021-12-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
NSCLC
chemotherapy
dormancy and reactivation
chromatin accessibility
transcription factors
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253121001876

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http://www.sciencedirect.com/science/article/pii/S2162253121001876

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