Study of cellular heterogeneity and differential dynamics of autophagy in human embryonic kidney development by single-cell RNA sequencing

Study of cellular heterogeneity and differential dynamics of autophagy in human embryonic kidney development by single-cell RNA sequencing

Abstract Background Autophagy is believed to participate in embryonic development, but whether the expression of autophagy-associated genes undergoes changes during the development of human embryonic kidneys remains unknown. Methods In this work, we identified 36,151 human renal cells from embryonic...

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Bibliographic Details
Main Authors: Chen Wen-jin, Pan Xiu-wu, Chu Jian, Xu Da, Chen Jia-xin, Chen Wei-jie, Wang Lin-hui, Cui Xin-gang
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Cancer Cell International
Subjects:
Human fetal kidney development
Autophagy
Single cell RNA sequencing
Heterogeneity
Wilms tumor
Online Access:https://doi.org/10.1186/s12935-021-02154-w

Internet

https://doi.org/10.1186/s12935-021-02154-w

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