Native α-Synuclein, 3-Nitrotyrosine Proteins, and Patterns of Nitro-α-Synuclein-Immunoreactive Inclusions in Saliva and Submandibulary Gland in Parkinson’s Disease

Native α-Synuclein, 3-Nitrotyrosine Proteins, and Patterns of Nitro-α-Synuclein-Immunoreactive Inclusions in Saliva and Submandibulary Gland in Parkinson’s Disease

<i>Background.</i> Salivary α-synuclein (aSyn) and its nitrated form, or 3-nitrotyrosine-α-synuclein (3-NT-αSyn), hold promise as biomarkers for idiopathic Parkinson’s disease (IPD). Nitrative stress that is characterized by an excess of 3-nitrotyrosine proteins (3-NT-proteins) has been...

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Bibliographic Details
Main Authors: Emilio Fernández-Espejo, Fernando Rodríguez de Fonseca, Juan Suárez, Eduardo Tolosa, Dolores Vilas, Iban Aldecoa, Joan Berenguer, Fátima Damas-Hermoso
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Antioxidants
Subjects:
parkinson
α-synuclein
saliva
nitration
nitrative stress
lewy-type
Online Access:https://www.mdpi.com/2076-3921/10/5/715

Internet

https://www.mdpi.com/2076-3921/10/5/715

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