Association of IL18 gene polymorphisms (positions -656 G/T, -137 G/C and +105A/C) with Kala-Azar

Background & Objective: Host resistance to Leishmania infection is mediated by cellular immune responses leading to macrophage activation and parasite killing. IL-18 known as interferon-γ inducing factor, stimulate IFN-γ production by T-cells. According to the important role of IL-18 in defense...

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Bibliographic Details
Main Authors: Yaser Mansoori, Ali Moravej, Sohrab Najafipour, Seyed Amin Kouhpayeh, Mohammad Hasan Meshkibaf, Abbas Abdollahi, Manochehr Rasouli, Ghader Allahverdi
Format: Article
Language:fas
Published: Fasa University of Medical Sciences 2012-09-01
Series:Journal of Fasa University of Medical Sciences
Subjects:
Online Access:http://journal.fums.ac.ir/browse.php?a_code=A-10-1-24&slc_lang=en&sid=1