Effect of a Selective Progesterone Receptor Modulator on Induction of Apoptosis in Uterine Fibroids In Vivo

Aim. To determine if hormonal treatment induces apoptosis in uterine fibroids. Methods. Immunohistochemical examination of fibroid tissue, using avidin-biotin complex and cleaved caspase-3 antibody for detecting apoptosis, was performed in premenopausal women who underwent 12-week treatment with ora...

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Bibliographic Details
Main Authors: Petr Horak, Michal Mara, Pavel Dundr, Kristyna Kubinova, David Kuzel, Robert Hudecek, Roman Chmel
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:International Journal of Endocrinology
Online Access:http://dx.doi.org/10.1155/2012/436174